Medibrane utilizes various technologies and, where needed, combines multiple techniques to achieve the precise results required for each device or structure.


Surface treatment

Surface treatment

Preparing the device’s surface is essential for obtaining good adhesion of the coating or of the implantable device. We implement the following pre-treatment surface techniques:

Grit-blasting: By forcibly propelling a stream of sand at high pressure against the stent’s metallic surface, the smooth surface becomes porous, which improves the adhesion of the coating to the surface.

Corona treatment (Air plasma): When utilizing this technique, a low-temperature, high-voltage electrical discharge is applied to an electrode that has a sharp tip, causing corona plasma to form at the tip. A linear array of electrodes is used to create a curtain of corona plasma, which modifies the stent’s surface.

Chemical treatment: This highly-effective method uses strong acids, alkalis, or mixtures of oxidants which remove thin layers of the surface, resulting in roughening of the surface, as well as causing surface porosity, which facilitates adhesion of the coatings.

Bonding molecules: In this technique, a base coating layer is created from bonding molecules, which one side adheres to the substrate, while the other side adheres to the coating.


Dip coating and molding

Dip coating and molding

Utilizing state-of-the-art machinery and precisely designed manufacturing processes, we are able to control temperature, humidity and viscosity, and achieve high manufacturing yield, while overcoming the potentially problematic aspects of this techniques, such as ununiformed coating, bubbles, coating adhesion and high defect rate.

Advantages over other techniques:

  • Fast prototype development
  • Cost effectiveness
  • Coatings with wall thickness of between 20-100 microns
  • Coating Tolerance: ± 10 microns

 


Spray coating

Spray coating

The spray coating technique utilizes ultrasonic nozzles, providing the ability to control the properties of the coating, which makes it easy to adapt it to applications that require thin uniform coating.

Advantages over other techniques:

  • Easy shaping of sprayed patterns, resulting in precise coating applications
  • Highly uniform surfaces are required particularly for cardiovascular devices, whereas rough, uneven surfaces can cause turbulation and thrombosis
  • Solvents are highly sensitive to dipping, and spray coating used instead
  • Highly controllable spray produces reliable, consistent results
  • Coating wall thickness: 10-100 microns
  • Coating Tolerance: ± 3 microns